And they mightve spent the last 20 of those years in an unbelievable state of misery. I dont do such silly things anymore. I think there [are] basically three ways that we can approach dealing with this: One of these is through psychotherapy, pharmacotherapy, and then behavioral therapy, which Im an overwhelming proponent of in particular a type of behavioral therapy called Dialectical Behavioral Therapy or DBT. Dr. Peter Attia. This mask versus that mask? Thats actually a billion dollar question. For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimers disease, and type 2 diabetes. I lived in Boston. Peter Attia Book Recommendations (38 Books) Peter Attia is a Canadian-American physician known for his medical practice that focuses on the science of longevity. And so, to answer your question, Steve, I am still incredibly bearish on sugar. Now, whether its another SARS coronavirus or an influenza virus or another virus, I dont know. While it's easy for me to say, I implore you to keep fighting back and never . That was painful to watch. I took out a piece of Nicorette gum and I started chewing. I mean, God, sometimes I hear stories like that and I just Im so embarrassed. It was about 10 things. So you have this starvation ketosis, nutritional ketosis. ", "Are We Fighting The Wrong Battle In The Obesity War? points on that day. People I (Mostly) Admire is part of the Freakonomics Radio Network, and is produced by Freakonomics Radio and Stitcher. So I think its a problem thats sub one hundred million dollars. Peter Attia talks with Steve Levitt about the problem with immortality, whats missing from our Covid response, and why nicotine is underrated. So it wasnt one thing, Steve. And when my daughter was born, I ended up getting a type of medical test that had a finding that no one in their mid-thirties should have. When it comes to chronic and life-threatening diseases, Dr. Peter said it comes down to three major things: So the big three are, in order, atherosclerotic disease so thats vascular disease, meaning heart disease and stroke. He explains the evolutionary drive to go from single-cell to multicellular life and unpacks the four different types of cell-based therapies and the problems they are attempting to solve. Peter's current diet can simplified into 3 "rules": Time Restricted Feeding Avoid Sugars, High Fructose Corn Syrup & Junk Food No Restriction on Healthy Starches and Vegetables 1) Time Restricted Feeding At the low end, Peter fasts between 14 - 16 hours each day, and at the high end, he fasts between 20 - 22 hours. ATTIA: Correct. The biggest risk, by the way, is probably mass vaccination. Without your financial help, this blog is in critical danger of not surviving. So my hours from 11:00 at night until like 5:00 in the morning, in a cold apartment. My practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). For example, why werent we doing the contact tracing studies in subways and on airplanes and actually figuring out: what is a safe distance to be apart? But I get a little bit worried that I dont know how to prepare them for a world that I dont understand. Hes one of the most intelligent, curious, compassionate people Ive ever met. He is willing to entertain any hypothesis. When we start to experience those mental health issues, we die in a sense. Lets dive in! Bring everyone together in one space with Microsoft Teams! Explore the list of the most recommended book titles suggested by Peter Attia . Dr. Peter Attia and Dr. Andrew Huberman discuss the best exercises for health and longevity.Dr. Why werent we immediately engaging in a whole bunch of experiments that would very rapidly get us answers to questions that would enable us to decide what to do? So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? Peter Attia, MD, is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. No, the short answer is, Im still trying to make sense of this as well. And during all of this intentional exercise, Dr. Peter has one thing in mind: his Centenarian Olympics. Youll be able to read more about this in Dr. Peters book when it comes out, but for now, I can tell you that the Centenarian Olympics is a series of activities that Dr. Peter wants to be able to do when he turns 100. I just didnt care if I was alive or dead, even though I wasnt even particularly tired. And that work ethic came from this belief that I actually dont think is that healthy. I really enjoy his take on things, his clarity, the brilliant guests he has on, and how out of my depth he is.. And actually, my model ended up working really well, but I was basically threatened that Id be fired if I ever did it again. funding for the rest of your life.. Its the common factor behind all three biggest causes of death Type 2 diabetes. Those three effectively make up three quarters of deaths of people who dont smoke. , Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. But do you have advice for young people who are trying to find their path in the world? If anything, I might even be more concerned with sugar, especially in its liquid form. All contents Freakonomics. Thank you so much for joining me today! Yesterday, I just finished a three-day fast. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. Dr. Peter Attia. And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. Dr. Peter Attia. I mean, not even hard to figure out if youre willing to do randomized experiments. document.getElementById( "ak_js_2" ).setAttribute( "value", ( new Date() ).getTime() ); Copyright 20122023 PA IP, LLC. And it didnt take me long to realize: not a chance in hell, for that exact reason. pick up the tab to really finish it, because this is a multi-year experiment. HOMA-IR and frailty (same study as #3 linked twice); The studies that use OGTT do not establish that glucose variability above 140 mg/dL is important; None show that the high glucose itself is causal or that reducing it via diet will improve outcomes. Fasting turns on a process called autophagy. Its great to live until youre 90 or 100 years old, but if you spend the last 20 or 30 years in so much pain or with a neurodegenerative disease like Alzheimers, youre not really enjoying those last few decades. So when you contrast living to 70 [and] spending 20 years in misery versus living to 75 with maybe two years in misery, it just doesnt even strike me as a trade-off. Dr. Peter Attia. So the other thing we always want to be optimizing around is how much fiber can you get? And then I would come home and I had a ritual that I would do 400 pushups every single night in sets of 50s and then go to bed and repeat. Autophagy is, as its name implies auto is self, phagy is eating so its when these cells eat themselves. ATTIA: Exactly. You went to McKinsey. So shes like, lets watch M.S.T.3.K. And by listening to this guy talk about subjects where I have a different point of view, hes sharpening my point of view and sometimes changing my point of view. Why is he telling us this? Whats important about that is the fructose molecule. All rights reserved. How does our mental health affect our longevity? And so I want to challenge you to do that. I want to be able to pull myself out of a pool where theres a one-foot gap between the water and the curb. is part of the Freakonomics Radio Network, and is produced by, and Stitcher. [8][9] Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. But I still stand by the benefits of nicotine. What outcome data are there to show that going above 140 mg/dL in a normal glucose excursion is harmful? I mean, this is not an unethical thing to do. Dr. Peter says there are four main ways to do it. Aside from preventing chronic diseases like Type 2 diabetes, how can we extend our healthspans to become, as Dr. Peter put it, kick-ass 100-year-olds? to do just that, Dr. Peter structures his exercise around four main pillars: My training is very specific, but now it is fundamentally organized around four pillars: Stability, strength, mitochondrial or aerobic efficiency, and anaerobic performance. Dr. Peter Attia. So I went, three days and just had water. The owner of this blog reserves the right to edit or delete any comments submitted to the blog without notice. Peter Attia has dedicated his medical career to investigating the relationship between nutrition, obesity and diabetes. LEVITT: But when you say risk, you talk about risk of wasting the money? I think they often get confounded. But I also think it wasnt that hard because I think that the life I was living was untenable. But not too far behind it is cancer. Glucose is such an important molecule for energy that if we were to go more than about a day and a half without eating, we would begin rapidly destroying our muscle mass in an effort to produce enough glucose to satisfy our brain, which would further impair our ability to forage for food. Dr. Peter Attia is a physician focusing on the applied science of longevity. My guest today is physician Dr. Peter Attia. Physician. His practice focuses on the applied science of longevity. [5] He spent two years at the National Cancer Institute (NCI) at National Institutes of Health (NIH), in Bethesda, Maryland as a surgical oncology fellow under Steven Rosenberg. LEVITT: And then you became obsessed with nutrition. Science has proven time and again that staring at screens right before bed can drastically reduce our sleep. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. What Happened To Peter Attia. What do you do daily to live a longer and healthier life? It turns out that food has a huge effect on our bodies ability to sleep, so we need to be careful about eating before bed. I also had an additional conversation with Kevin Hall, PhD, one of the key researchers NuSI . And also, what hes going to talk about in this documentary is really complicated. that was typically done by putting your finger in the air and looking at which way the wind blows. And I want you to interrupt me every time you have a question.. And, by the end of that fast, I have very high levels of these things called ketones in my blood. It also impairs senescent cells or more likely impairs the secreting factors that are made by senescent cells. In 2018 Dr. Attia switched to a special type of magnesium called Slow-Mag. From 2012-2015, he . Now he's a physician focused on the science of longevity. ATTIA: What an obnoxious idiot I was. Lets talk a little bit about the difference between lifespan and healthspan because theres a really key distinction between them. Last week, Peter Attia wrote a criticism of Game Changers, where he presented the argument (long repeated him) that nutritional epidemiology is fundamentally flawed. Your body naturally creates glucose in your liver, so when you eat and consume extra glucose, your body sends it to your muscles, and you use it as energy. Weve developed treatments for all kinds of conditions from acne to cancer, and weve greatly expanded our lifespans. Also, I had a big fight with one of the physicians at Hopkins whos super respected and amazingly prominent. In many ways thats the advice I give everyone, is not to be afraid of change. Comments containing language or concepts that could be deemed offensive will be deleted. Readdressing Dietary Guidelines - Dr. Peter Attia. But the point is, without making these proactive changes, they mightve lived only until 70. If you learned something today, please share it with us! And in the meantime, if youre ready to learn how to live to be over 100 and prevent chronic diseases, join me on Episode 1,045 with Dr. Peter Attia! But life isnt really about necessarily being the master of something. Theres days when I really feel like Im getting left behind and the train is so far ahead and Im never going to catch up. LEVITT: Thats intense. @bariweiss. But I have to say, hes also completely, totally insane. Most people, when they think of death, think of what we call cardiopulmonary death or what Im calling death-certificate death. But probably 80% of people have actually died one of the other deaths before they die a cardiopulmonary death. I rarely have a conversation with Peter in which he doesnt introduce me to something Ive never thought about before. But it could put a slightly different interpretation on it. And so when I decided to leave, my first thought was actually to go to business school, because I really missed doing quantitative problem-solving. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. And to me, we want to minimize that gap, right? And when it comes to naps, Dr. Peter says theyre fine, as long as they dont disrupt your sleep at night. And then take a little step further, and you reach neurodegenerative disease, of which Alzheimers disease is far and away the most common and also the most rapidly increasing. But when we sleep, its best for our bodies to be cold when we sleep cooler, we get more rejuvenating sleep. LEVITT: Yeah. . And then you have to have a third project, which is like 75 percent done. But to accomplish that goal, we have to learn how to prevent chronic diseases. The latter is just a liquid mixture of them in a slightly different ratio that favors fructose, which makes it a little sweeter. Peter Attia is a physician focusing on the applied science of longevity. Right? And then youd just be guaranteed to get N.S.F. No government funds at all, is that right? Attia speaks at the Ancestral Health Symposium in 2013, "A Manhattan Project To End The Obesity Epidemic", "Is it what we eat? So, Ive done a lot of different things and that makes me a master of nothing. If I just took 20 guys like you and took them from eight hours a night to four hours a night for two weeks and then did these glucose tolerance tests, I could reduce [their] glucose disposal by 50%. That sort of irked me. Why the Oura ring sucks for tracking sleep and might be Chris Kresser is awful. So that comes in mostly two forms in the United States, which is sucrose, or table sugar, which is that white granular powder, or high fructose corn syrup, which is a syrupy liquid approximation of that. And then at lunch we would go to the University of Toronto I grew up in Toronto so wed go to University of Torontos weight room and do our really heavy lifting. But there was a brutal concussion I had. Have any hacks how to do? His practice also focuses on elements such as diet, sleep, exercise, and, physiological aspects that promote The House of Representatives is not exactly filled with people who understand science. This is a tragedy. And Im the provocateur who helps de-risk these things. And in particular, I dont know if youve looked at naps at all, but theres some new research that suggests that in terms of afternoon productivity, naps have an incredible impact. LEVITT: And how much fasting does a person have to do to start getting those benefits? Kudos to @SnoozyWeiss. Maybe it was partly the placebo effect of all your happy stories about it. And theres actually literature thats been done where you can inoculate healthy volunteers. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. But I just decided death would be welcome. [7] Attia co-founded and served as President of Nutrition Science Initiative (NuSI) with Gary Taubes in 2012. And you said, Well, Im allergic to sugar. And with a great deal of curiosity, she said, What happens to you when you eat sugar? And you looked at her completely deadpan. Its easy to be an armchair quarterback, but its still hard for me to realize why we didnt make a greater effort to ramp up testing quicker. And you were like, Whats that? And I was like, Oh, I chew Nicorette gum. And you asked me if I was a smoker. He also. And I am so humbled by how bad I am now. After medical school, Attia spent five years at the Johns Hopkins Hospital in Baltimore, Maryland as a general surgery resident. But I tried to build a mathematical model to address a problem in the I.C.U. According to Tools of Titans, Attia takes 600 to 800 mg per day of magnesium, alternating between mag sulfate and mag oxide. With over 50 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimers disease, cancer, mental health, and much more. To me the more important question, Steve, and the one I spend more time thinking about, is: what do you do next time around? It promises to be one of the most important books you'll ever read." Steven D. Levitt, New York Times bestselling author of Freakonomics "In Outlive, Peter Attia explores the science of not just . And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. , Most people, when they think of death, think of what we call cardiopulmonary death or what Im calling death-certificate death. But probably 80% of people have actually died one of the other deaths before they die a cardiopulmonary death. Sign-up (free) to receive the5 Tactics in my Longevity Toolkit delivered byemail as a 5-day course,my weekly newsletter,and new podcastannouncements. Dr. Peter focuses on the applied science of longevity, the extension of human life, and overall well-being. Lets watch this thing instead. And shes like, Who is this guy? And I said, Look, I dont agree with half the things this guy says, but he is categorically one of the smartest dudes ever. Its one of the three vetted sleep surveys that really can give us insight into your sleep. The Canadian-American physician trained at the Johns Hopkins Hospital in general surgery for 5 years and won a number of prestigious awards, including "Resident of the Year."Currently, he hosts a weekly, deep-dive podcast called The Drive. Steve, we should have you take the Epworth Sleep Survey. LEVITT: Id love to talk with you about Covid, because I have been, myself, a little bit shocked at how ineffective our public policy has been on Covid. LEVITT: Yeah, for sure. LEVITT: So, tell me what are your current feelings towards sugar? LEVITT: Thats been my reaction exactly, is, the answer to every one of the questions you just posed is completely and totally knowable. According to his website, Attia is "a Stanford/Johns Hopkins/NIH-trained physician focusing on the applied science of longevity, the extension of human life and well-being." These credentials have given Attia unparalleled clout (along with David Sinclair) in this niche of influencers. 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